November.2019
3 Mins
Periodontal Disease Associates with Arterial Inflammation via Potentiation of a Hematopoietic–Arterial Axis
Periodontal Disease Associates with Arterial Inflammation via Potentiation of a Hematopoietic–Arterial Axis
Periodontal Disease Associates with Arterial Inflammation via Potentiation of a Hematopoietic–Arterial Axis
Ishai A, Osborne MT, El Kholy K, Takx RAP, Ali A, Yuan N, Hsue P, Van Dyke TE, Tawakol A
JACC Cardiovasc Imaging.
Summary
Background
People with periodontal disease have a higher risk of cardiovascular disease, but the biological pathway behind this link is not well understood.
Approach
Using 18F-FDG PET/CT imaging, the researchers measured inflammation in the periodontium and in the arteries, together with the activity of the blood-forming (hematopoietic) tissue in the bone marrow.
Findings
Greater periodontal inflammation was associated with greater arterial inflammation, and this relationship appeared to involve increased hematopoietic activity.
Conclusion
Periodontal inflammation may promote arterial inflammation by stimulating the bone marrow's production of inflammatory cells, a possible pathway between gum disease and cardiovascular disease.
Keywords
periodontal disease, arterial inflammation, cardiovascular risk, hematopoietic activity, FDG-PET/CT, systemic inflammation
No technician, no engineer.
Just surgical planning by one dentist for another.
No technician, no engineer.
Just surgical planning by one dentist for another.
No technician, no engineer.
Just surgical planning by one dentist for another.
November.2019
3 Mins
Periodontal Disease Associates with Arterial Inflammation via Potentiation of a Hematopoietic–Arterial Axis
Periodontal Disease Associates with Arterial Inflammation via Potentiation of a Hematopoietic–Arterial Axis
Periodontal Disease Associates with Arterial Inflammation via Potentiation of a Hematopoietic–Arterial Axis
Ishai A, Osborne MT, El Kholy K, Takx RAP, Ali A, Yuan N, Hsue P, Van Dyke TE, Tawakol A
JACC Cardiovasc Imaging.
Summary
Background
People with periodontal disease have a higher risk of cardiovascular disease, but the biological pathway behind this link is not well understood.
Approach
Using 18F-FDG PET/CT imaging, the researchers measured inflammation in the periodontium and in the arteries, together with the activity of the blood-forming (hematopoietic) tissue in the bone marrow.
Findings
Greater periodontal inflammation was associated with greater arterial inflammation, and this relationship appeared to involve increased hematopoietic activity.
Conclusion
Periodontal inflammation may promote arterial inflammation by stimulating the bone marrow's production of inflammatory cells, a possible pathway between gum disease and cardiovascular disease.
Keywords
periodontal disease, arterial inflammation, cardiovascular risk, hematopoietic activity, FDG-PET/CT, systemic inflammation
No technician, no engineer.
Just surgical planning by one dentist for another.
No technician, no engineer.
Just surgical planning by one dentist for another.
No technician, no engineer.
Just surgical planning by one dentist for another.